Liposomes: Methods and Protocols, Volume 1: Pharmaceutical Nanocarriers

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With nearly one hundred years of intensive study, lipids have proven to be a vital and ever-more-promising area of cell biological research. In Liposomes: Methods and Protocols, leading experts in the related fields explore cutting-edge experimental methods involving all aspects of lipids as essential components of the cell membrane. Volume 1: Pharmaceutical Nanocarriers focuses on the state-of-the-art aspects of developing liposome-based nanoscale drug delivery techniques, delving into the depths of the emerging field of pharmaceutical and biomedical nanotechnology. As a volume in the highly successful Methods in Molecular Biology™ series, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Comprehensive and authoritative, Liposomes: Methods and Protocols promises to be an essential source of practical know-how for every investigator, young and seasoned alike, whose research area involves in one way or another phospholipids, glycolipids, or cholesterol.

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Dendrimer-Based Nanomedicine

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In recent decades, dendrimers — free-shaped synthetic macromolecules — have garnered a great deal of scientific interest due to their unique molecular nanostructure. Used in a variety of scientific applications, the use of dendrimers is now widely regarded as a safer, more precise, and more effective way to practice medicine.

This book compiles and details cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological Sciences, who are currently revolutionizing drug delivery techniques through the development of engineered nanodevices. Edited by Istvan J Majoros and James Baker, Jr., two prominent nanotechnology researchers, this book will appeal to anyone involved in nanotechnology, macromolecular science, cancer therapy, or drug delivery research.

Contents: Targeted Drug Delivery in General, New Technology in Medicine (B B Ward & J R Baker, Jr.); General Carriers for Drug Delivery (T H Dunham et al.); Poly(amidoamine) Dendrimer Synthesis and Characterization (I J Majoros & D E Carter); Optical and Biophotonic Applications of Dendrimer Conjugate (J Y Ye & T B Norris); Dendrimer Conjugates for Cancer Treatment (I J Majoros et al.); Biological Application of PAMAM Dendrimer Nanodevices in vitro and in vivo (T P Thomas & J F Kukowska-Latallo); Dendrimer-based Targeted Apoptosis Sensors for Medical Application (A Myc et al.); MRI Using Targeted Dendrimer Contrast Agents (S D Swanson & C R Williams); Nanoparticle Membrane Interactions: Mechanism for Enhanced Permeability (S Hong et al.); Computer Simulations of Dendrimers (S K Kandasamy et al.); Dendrimer-Entrapped and Dendrimer-Stabilized Metal Nanoparticles for Biomedical Applications (X-Y Shi & S H Wang).

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