USPTO allows Regulus Therapeutics’ claims covering methods of antagonizing miR-181a for regulating immune response

USPTO allows Regulus Therapeutics’ claims covering methods of antagonizing miR-181a for regulating immune response
Regulus Therapeutics Inc. announced today that the United States Patent and Trademark Office (USPTO) has allowed claims in U.S. Application Serial No. 11/977,506 covering methods of antagonizing miR-181a to regulate immune response. This patent is owned by Stanford University and licensed exclusively to Regulus. miR-181a has been shown to regulate the response of immune cells, such as T …

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Nanowires and Nanocrystals for Nanotechnology

Google Tech Talks September 12, 2006 Yi Cui is an assistant professor in the Materials Science and Engineering Department at Stanford University. He is a recipient of the Technology Review World Top 100 Young Innovator Award. He received his phd degree from Harvard University working with Prof. Charles Lieber. He received his BS degree from Univ of Science and Technology of China. ABSTRACT Nanowires and nanocrystals represent important nanomaterials with one-dimensional and zero-dimensional morphology, respectively. Here I will give an overview on the research about how these nanomaterials impact the critical applications in faster transistors, smaller nonvolatile memory devices, efficient…

Rechargeable Batteries – Looking Forward

In 2007, assistant professor Yi Cui and colleagues at Stanford University’s Department of Materials Science and Engineering discovered that using silicon nanowires as the anode in rechargeable batteries increases the volumetric charge density of the anode by up to a factor of 10. This is significant because it offers an opportunity to use new types of active components for the batteries.

The active components in a secondary cell are the chemicals that make up the positive and negative active materials, and the electrolyte. The positive and negative are made up of different materials, with the positive exhibiting a reduction potential and the negative having an oxidation potential. The sum of these potentials is the standard cell potential or voltage.

In primary cells the positive and negative electrodes are known as the cathode and anode, respectively. In rechargeable cells the positive electrode is the cathode on discharge and the anode on charge, and vice versa for the negative electrode.

Already, several alternatives to rechargeable batteries exist or are under development. For transportation, uninterruptible power supply systems and laboratories, flywheel energy storage systems store energy in a spinning rotor for reconversion to electric power when needed; such systems may be used to provide large pulses of power that would otherwise be objectionable on a common electrical grid. For uses like portable radios and flashlights, rechargeable batteries may be replaced by clockwork mechanisms or dynamos which are cranked by the user to provide power.

A future development could be ultracapacitors for transportation, using a large capacitor to store energy instead of the rechargeable battery banks used in hybrid vehicles. One drawback to capacitors compared with batteries is that the terminal voltage drops rapidly; a capacitor that has 25% of its initial energy left in it will have one-half of its initial voltage. However, there are potential benefits in cycle efficiency, lifetime, and weight compared with the rechargeable batteries system.

U.S. Scientists use nano-coating made of paper-based battery

?China Coating Online News U.S. scientists at Stanford University, made the use of nanotechnology-based fast-ordinary office paper for ultra-lightweight, flexible battery or super capacitor. Related Articles published in this week’s U.S. “National Academy of Sciences” on-line edition.

Materials Science and Engineering at Stanford University assistant professor Yi Cui (phonetic) said it would provide a paper covered with silver nanowires with carbon nanotubes and coating raw materials can be turned into a good conductive energy storage device. He said that these nano-materials with a diameter of a small three-dimensional structure, which enable nano-materials, dressing more closely attached to the surface of the paper fibers, making a more durable battery or super capacitor. This paper can achieve a super capacitor, or 40000 times charge-discharge cycles, or at least comparable to the number of lithium battery charge and discharge an order of magnitude higher. The nano-materials, more efficient charge transfer can also make it more advantages than conventional capacitors, the effect would be better.

Research team tried a plastic substrate made of nano-materials for energy storage devices, dressings and paper and as a close bond resistance, this paper as the base of the battery than the battery more durable plastic substrate. More importantly, the paper batteries are not afraid of crumple and fold, or even their being immersed in acidic solution, it will not affect performance, but also to effectively reduce production costs.

Cui Yi, said paper-based flexibility to achieve a variety of intelligent applications, such as brushes can be such a high electrical conductivity of the dressing smear on the wall above, and its fast becoming a large-scale energy storage device. When it with light-emitting diode (LED) and so connected, it can provide sufficient electricity for the LED source. In addition, this technology can be used for power distribution networks, will generate surplus electricity at night up centralized storage and ease pressure on electricity during the day time peak. In the wind farms and solar energy storage systems can also achieve similar applications. It is worth noting that the paper super capacitor may also be used to electric or hybrid vehicles into. Two kinds of cars depends on the rapid transmission of electricity, while the paper capacitor high ratio of surface area and volume, which created its presence in the automotive application of a great advantage.

As a leader in nanotechnology, the University of California at Berkeley professor of chemistry Peidong Yang, said the technology’s ability to achieve in the short term commercial potential. He believes that this technology will not just be limited to the field of energy storage devices, and its low cost and flexible properties make it fit with any electrical device electrode, the prospects quite broad. More importantly, we can use the most common life of the paper as a substrate, through a simple process,  apple ibook g4 14-inch series laptop battery made of conductive features strong, which will fundamentally nanotechnology will be linked with people’s daily lives.

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