Nanomaterials and Nanosystems for Biomedical Applications

Product Description

“Nanomaterials and Nanosystems for Biomedical Applications” brings together under a single cover various aspects of functional bioengineered materials and nanostructured biomaterials including commonly used implants and sustained release nanodevices. The book includes expert reviews on the advances and current problems associated with the implants and nanodevices along with their applications in medicine, pharmaceutics, cancer therapy, gene transfer and drug delivery. The editor, M. R. Mozafari (PhD), has been working in the field of nanobiotechnology for the past 14 years and has produced more than 60 publications. The book also describes the key research parameters pertaining to major technologies employed in the field. To put it in perspective, all important aspects dealing with the chemistry, physics, biology and engineering of nanostructured biomaterials and their applications in nanobiotechnology are covered.

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Drug Delivery System

Drug delivery refers to the delivery of a pharmaceutical substance to human beings or animals. Modes of delivery include oral, nasal and rectal. However, administration of drugs through these modes may lead to terrible conditions.

Therefore, physicians prefer to deliver several peptides and protein drugs through injections.

To work efficiently, the drugs have to act in certain controlled manner to distribute the drug in the body. Targeted drug delivery takes place when the drugs remain active within a specific region of the body. Targeted delivery is important when the drugs need to have an effect on rapid increase of cells that lead to cancerous tissues.

Recent attempts in the area of drug delivery include, advance in intended delivery where the drugs are only active in the targeted area of the body (for instance, in cancerous tissue) and sustained-release formulations wherein the physician releases the drug over a period in a certain controlled manner.

The main aim of drug development is to discover drugs that are more effective and help to cure several symptoms of medical condition or illness. Drug development is often required to discover the chemical properties of latest substances, their strength and chemical composition. It is also necessary for the process of drug development to meet the regulations laid down by the authorities who certify drugs.

Nanotechnology:

All around the world, physicians attempt to find methods for more efficient drug delivery and drug development.

Nanotechnology is an effective method developed in the recent years. This mechanism simply makes possible for the drugs to saturate cell walls. The nanotechnology methods play a vital role in pharmaceutical industry.

The new drug delivery system might help alleviate some of the concerns of the pharmaceutical industry as it has answers to:

1. Better targeting ability: Then, patients will have to take low doses and therefore, there will be fewer side effects.

2. Reduction of manufacturing costs

3. Solubility enhancements

In very simple terms, drug delivery system is a process in which a bioactive agent is released at a specific site and at a specific rate. The drug delivery industry is evolving rapidly for the benefit to the human community.